Laboratory for
Redox Regulation

Welcome to the Laboratory for Redox Regulation

The research in the laboratory is focused on the functional consequences of oxidative stress and reactive oxygen species (ROS) on biological systems. The role of oxidative stress in disease became apparent in the mid 50's and it is now well recognized that a number of diseases are associated with an increased level of ROS. However, research within the last decades has shown that ROS - maintained at a normal physiological level - regulates diverse physiological processes including signalling, transcription, translation and protein folding. This type of regulation is referred to as redox regulation.

The aim of our research is to gain further insight into the mechanistic roles of ROS in biological systems in order to understand how redox homeostasis is maintained in the body. This knowledge will support the further understanding of how ROS impacts biological processes that may result in the development of disease.